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Real Science Teaching. Real Classroom Experience.

I’m Amy Brown, a veteran high school biology and chemistry teacher, wife, and mom who understands the daily reality of lesson planning, grading, meetings, and everything in between. I know what it feels like to have too much to do and not enough time to do it.

After decades in the classroom, I’ve created rigorous, classroom-tested biology and chemistry resources that save you planning time while still delivering strong, meaningful science instruction. Every lab, activity, and lesson is designed to move students beyond memorization and into real scientific thinking.

If you want your students excited about science and thinking deeply without spending your entire weekend planning, you’re in the right place.

Amy Brown Biology and Chemistry Teacher

“I just love getting kids hooked on science.”

Catalase Enzyme Lab: Liver and Potato Experiment for High School Biology


catalase enzyme lab with liver and potato showing oxygen bubbles from hydrogen peroxide reaction free biology lab activity


This catalase enzyme lab uses liver and potato tissues to demonstrate enzyme activity in a clear and engaging way for high school biology students. In this catalase lab experiment, students observe how catalase breaks down hydrogen peroxide into water and oxygen, producing visible bubbles that show enzyme activity in real time. This enzyme lab is an excellent hands-on activity for teaching enzyme function, enzyme specificity, and biological reactions.

This catalase enzyme lab is one of the most popular enzyme experiments for teaching enzyme activity and is easy to set up using common classroom materials.

You can download this free catalase enzyme lab activity here to use with your biology students.

What concepts are covered and reinforced?

1.  Enzymes speed up the rate of biological chemical reactions.
2.  The same enzymes are found in both plant and animal cells.
3.  Enzymes are highly specific for the reaction they catalyze.
4.  Enzymes carry out their functions more efficiently than catalysts.
5.  Enzymes can be denatured by excessive heat.

Why Catalase Is Found in Both Plant and Animal Cells

Catalase is an enzyme that is commonly found in both plant and animal tissues. Its function is to break down hydrogen peroxide, a toxic byproduct of cellular respiration and other metabolic reactions, into water and oxygen. Because hydrogen peroxide is continuously produced inside living cells, catalase plays an essential role in protecting plant and animal cells by preventing harmful buildup of this toxic substance.


Manganese dioxide is a non-biological catalyst. Like enzymes, catalysts speed up chemical reactions, but unlike enzymes, catalysts are not specific to a single reaction. This comparison helps students understand the unique properties of enzymes and how enzyme activity differs from inorganic catalysts.  

This catalase enzyme lab uses common materials to demonstrate enzyme activity in plant and animal tissues.

Materials for the Catalase Enzyme Lab Using Liver and Potato


  • Fresh plant and animal tissue (Potato and Liver)
  • Boiled animal tissue (Liver)
  • 3% hydrogen peroxide
  • Manganese dioxide
  • Test tubes and test tube rack
  • Sand
  • Mortar and pestle

Catalase is found in all eukaryotic cells, which is why this enzyme lab works using many types of fresh, living tissues. Liver is an excellent source of catalase from animal cells, and potato tissue provides a reliable source of catalase from plant cells. Comparing catalase activity in liver and potato tissues allows students to observe enzyme activity in both plant and animal cells. This comparison helps students understand that catalase is present in many different living tissues and plays an essential role in protecting cells.


What Happens When Catalase Breaks Down Hydrogen Peroxide?

Students will observe bubbles forming as catalase breaks down hydrogen peroxide into water and oxygen gas. These bubbles are oxygen released during the catalase enzyme reaction. Fresh liver and potato tissues produce a strong bubbling reaction because they contain active catalase, while boiled tissues produce little or no reaction because heat has denatured the enzyme.


Students absolutely love this catalase enzyme lab because they can immediately observe enzyme activity as bubbles of oxygen form during the reaction. 

This free catalase enzyme lab activity includes complete student instructions and a teacher guide to help you easily implement this engaging enzyme experiment in your classroom.


Frequently Asked Questions About the Catalase Enzyme Lab

Why do both plant and animal cells contain catalase?

Catalase is found in both plant and animal cells because all living cells produce hydrogen peroxide during normal metabolic processes. Catalase protects cells by breaking hydrogen peroxide down into water and oxygen.

Why is liver often used in catalase labs?

Liver cells contain large amounts of catalase because the liver plays a major role in detoxification. This makes liver an excellent tissue for demonstrating catalase enzyme activity in lab experiments.

Why do boiled tissues show little or no catalase activity?
Boiling denatures the catalase enzyme, changing its structure so it can no longer function properly. This prevents catalase from breaking down hydrogen peroxide.

What causes the bubbles in a catalase enzyme lab?
The bubbles are oxygen gas released when catalase breaks down hydrogen peroxide into water and oxygen. This visible reaction demonstrates enzyme activity.

Related Blog Posts About Enzymes and Enzyme Labs:

Everything About Enzymes!

The Affect of the Enzyme Amylase on Starch

Why Do Living Cells Need Buffers? A Homeostasis Lab for Biology

Another engaging activity to include in your biochemistry unit is this food testing lab for organic compounds, where students identify sugars, starches, proteins, and lipids using indicator tests.

Related Enzyme Labs and Biology Activities

These enzyme labs and biology activities help students further explore enzyme function, enzyme activity, and biochemical reactions in living cells.

Enzyme Lab: The Effect of pH on Living Cells

1 comment:

  1. This is very similar to elephant toothpaste! Such a fun experiment.

    Amy

    The Crazy Adventures of a University Grad

    ReplyDelete