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Real Science Teaching. Real Classroom Experience.

I’m Amy Brown, a veteran high school biology and chemistry teacher, wife, and mom who understands the daily reality of lesson planning, grading, meetings, and everything in between. I know what it feels like to have too much to do and not enough time to do it.

After decades in the classroom, I’ve created rigorous, classroom-tested biology and chemistry resources that save you planning time while still delivering strong, meaningful science instruction. Every lab, activity, and lesson is designed to move students beyond memorization and into real scientific thinking.

If you want your students excited about science and thinking deeply without spending your entire weekend planning, you’re in the right place.

Amy Brown Biology and Chemistry Teacher

“I just love getting kids hooked on science.”

Evolution and Classification Warm Ups and Interactive Notebook Pages

Do you love teaching about evolution or dread it?


I am the biggest biology nerd ever, so I love ALL of biology.  But I really, really, really love teaching about evolution, followed up with classification.  My first year biology students have very poor (and uninformed!!) ideas and knowledge about evolution.  For many of them, it is the first time they have been taught about it.  Others come with a lot of misinformation.

This makes for such a fun teaching situation!  Just for kicks, ask your students about their opinions on the topic of evolution BEFORE you teach them the unit. I am always amazed at their misconceptions and poor knowledge base.  When you have finished teaching your unit, ask the students again about their opinions.  I love that over the course of a couple of weeks the opinions of many will be changed, and the knowledge level of all has been increased.

And the best part?  There is never a dull moment in class.  I love the discussion and the questions and the arguing!  I love to see the wheels turning in their brains.

Since this material tends to be new for most of my students, I developed a set of 61 warm ups / bell ringers / interactive notebook pages to use during the unit.


There are so many ways to use these pages.  I have my students keep a "Biology Warm Up Notebook."  It is a perfect way to review and reinforce material from the previous day, and it is a fantastic classroom management tool. 

My students come in, grab the warm up and get right to work. By the time I have finished taking roll, answering questions, dealing with the "stuff" that we teachers always have to deal with, my students are settled down and are already hard at work. There are too many pages to be completed in class, so I often use them as homework assignments, and review guides for the unit test.

Keeping a "warm up" notebook provides a perfect way to
review for the semester exam or end of course testing.


Below is a table of contents.  The 61 pages include all of these titles.



Here is a look at format.....



As always, I hope you are having a terrific year with your students.

Links to all Warm Ups / Bellringers/ Interactive Notebook Topics:







DNA and RNA and Protein Synthesis: Warm Ups or Interactive Notebooks

There are so many possibilities for these interactive pages!

The concepts involved in a unit on DNA, RNA, and protein synthesis are difficult and complex. Although this is one of my most favorite topics to teach, I fully realize that some of my students will struggle and will have a hard time "visualizing" the information.

I began "dabbling" with the use of warm ups / bell ringers / interactive notebook pages at the end of last school year.  I was pleased with the results, but wished I had started my students on this path from the start of the school year.  So this year, I did.  I love the flexibility of the different ways they can be used:  Interactive notebooks, warm ups, bell ringers, exit slips, homework assignments, or short daily quizzes.

This set on DNA and RNA is actually the 5th set of these activity pages that I have completed. If interested, here are the previous blog posts on the other 4 sets:
Introduction to Biology: Great Classroom Management Tool
Biology Interactive Notebooks (Cell Structure and Physiology)
Ecology Warm Ups
Genetics Activities for Interactive Notebooks

I ended up with 35 student pages in this set on DNA and RNA.  They have a really good range in difficulty.  When taken in order, the first few pages are very basic, and they increase in complexity as you move through the entire set. Teachers of middle school students will find plenty of pages that are suitable for their students, and the high school teachers will find the advanced topics they need to move their students to a higher level.

The 35 pages have a good mix of question types.  Some pages require drawing, while others require more problem solving and critical thinking skills.  But the key element of every page is reinforcement and review of the concepts and details of protein synthesis.




Below you will find the titles of the 35 pages included in this product.

DNA and Replication Titles (14 pages):
·    The Early Experiments
·    The Basics of DNA Structure
·    Nucleotides
·    DNA: Label It!
·    Complete the Drawing
·    Can You Draw It?
·    DNA Structure
·    DNA Replication
·    A Detailed Look At Replication
·    Proofreading the DNA
·    Repairing the Damage
·    The Genetic Code
·    Deciphering the Code
·    Thinking Critically About DNA

RNA and Transcription Titles (8 pages):
·    Differences Between DNA and RNA
·    RNA: The Big Picture
·    Types of RNA
·    Overview of Transcription
·    Steps to Transcription
·    Transcription: Complete It!
·    RNA Processing and Editing
·    The Genetic Code

Translation and Protein Synthesis Titles (5 pages):
·    Overview of Protein Synthesis
·    Translating the Code
·    Translating the Code 2
·    Mutations
·    Mutations 2

Gene Expression Titles (3 pages):
·    Gene Expression in Prokaryotes
·    Gene Expression in Eukaryotes
·    Cancer


Genetic Engineering Titles (5 pages):
·    Changing the Living World
·    Manipulating DNA
·    Cell Transformation
·    Transgenic Organisms

·    Thinking Critically About Genetic Engineering



These are fantastic for your interactive notebooks.  


Thanks for stopping by my blog.  I hope you are having a wonderful school year!


Links to products in my TpT Store:
Introduction to Biology Warm Ups
Cell Structure and Physiology Warm Ups
Ecology Warm Ups
Genetics Warm Ups
DNA, RNA, and Protein Synthesis Warm Ups

"Meet and Teach" with these Fabulous Teacher/Authors!

What is the "Meet and Teach" eBook?

This is one eBook you are not going to want to miss! Recently, Brain Waves Instruction, Literary Sherri, and Getting Nerdy with Mel and Gerdy combined forces to compile three separate eBooks that are packed full of "ready to teach" lessons and pages.

Specifically, there are three different eBooks:  One for Science and Math, one for ELA, and one for Humanities.  Each eBook has contributions from 25 teacher/authors.  Each author was asked to submit two pages to the eBook. The first page is the "Meet" page.  You will find fun information about each teacher, such as their favorite things and why they love teaching their subject. The second page is the "Teach" page.  This page is a ready-to-print and ready-to-teach free item.  It has everything you need!  Simply print the page and start teaching.

Here is a sneak preview of the two pages I submitted to the eBook;



As you can see, the "teach" page above is ready to be printed and passed out to your students.  The pages are sample pages from my biology interactive and warm up notebooks.

There are some really fabulous ideas and free resources included in all three eBooks.  You will not be disappointed in this free download!

Ready to download your free eBooks?  Click on the images below to download the book of your choice, or all of them!






Onion Root Tip Mitosis Squash Preparation Protocol (Step by Step Chromosome Squash Method)

Onion root tip mitosis chromosome squash preparation showing onion bulbs growing roots, lab materials, and microscope images of mitotic cells


This post outlines a step by step onion root tip mitosis squash preparation protocol for biology teachers looking to prepare chromosome squash slides.

When you can smell the onions at the end of my hallway, you know it is time to study cell division and make chromosome squash slides. Even after more than 30 years of teaching, this remains one of my favorite biology labs. Students experience everything from frustration when a slide does not turn out to real excitement when they peer into the microscope and realize they made a good one.

What exactly is a chromosome squash?  

A chromosome squash is a slide preparation technique that uses actively dividing cells from an onion root tip to show the different phases of mitosis under a microscope.

How long is this lab?  

This lab takes several days to complete. A short amount of class time is needed to start the onion roots growing. After about five days, students cut the root tips. You should then allow at least two additional class periods for slide preparation and microscopy.

Are there safety precautions that should be followed?  

Yes. This lab requires the use of concentrated hydrochloric acid. It should be conducted in a well ventilated lab with access to a fume hood and an eye wash station. Students must wear safety goggles and lab aprons at all times.
Onion bulbs suspended in water with growing root tips for mitosis squash preparation

Onion Root Tip Mitosis Squash Preparation Protocol

Begin by purchasing onion sets from a local feed and seed store or a biological supply company. For variety, I typically use red, yellow, and white onions. The color of the onion does not affect the outcome of the lab, but students enjoy growing them, and the lab tables look great when they are full of sprouting onions.

Onion root tips showing areas of active cell division used for mitosis squash slides
The next step is to "plant" the onions. As you can see in the photo, you will need small plastic cups and toothpicks. A 50-mL beaker works well, also. Students insert three toothpicks into each onion to form a tripod and suspend the onion over a cup filled with water. This setup takes about 20 minutes of class time. Root tips are typically ready for use after about five days.

The root tip is a region of rapid cell division. As the root grows, cells divide continuously, making this tissue ideal for observing mitosis. Once the root tips reach a length of approximately one inch, use a razor blade to cut the roots away from the bulb. Place the root tips in 70 percent isopropyl alcohol. The alcohol kills and preserves the cells, and because many cells are actively dividing, they are often arrested in one of the phases of mitosis. The root tips must soak in the alcohol for at least 24 hours before slide preparation.

Onion root mitosis showing onion growing and when they are ready to use

Onion root tips showing areas of active cell division used for mitosis squash slides
Day 5:  Roots are long enough to be cut.

Ready to make the slide?  

It is important to forewarn students that this procedure is not perfect. Several attempts may be required before a slide is clear enough to observe the phases of mitosis. This trial and error is part of the learning process and helps students develop patience and laboratory skills.

To begin slide preparation, remove a root tip from the isopropyl alcohol and place it in a solution of hydrochloric acid and ethyl alcohol. After the appropriate amount of time, transfer the root tip to Carnoy’s solution. Next, place the root tip on a microscope slide and cover it with aceto-orcein stain. While the tissue is in the stain, students should finely chop the root tip using a razor blade. For best results, thorough chopping helps separate the cells.


materials needed for onion root tip chromosome squash protocol

Onion root tip chromosome squash lab protocol materials needed

The final step is the squash technique. Place a cover slip over the chopped root tip and apply gentle, even pressure with your thumb. This spreads the cells into a thin layer suitable for viewing under the microscope.

Place the prepared slide under the microscope and examine it for cells in the different stages of mitosis. Because this technique can be challenging, multiple attempts may be necessary before a clear slide is obtained.

When students finally observe a successful slide, the excitement in the lab is immediate and contagious. I encourage students to take photographs of their slides using their cell phones. While I have never quite mastered this skill myself, students are surprisingly good at capturing clear images.

Have fun teaching!

Frequently Asked Questions: Onion Root Tip Mitosis Squash Preparation

What is an onion root tip mitosis squash?
An onion root tip mitosis squash is a slide preparation technique that uses actively dividing cells from onion root tips to observe the phases of mitosis under a microscope.

What materials are needed for an onion root tip chromosome squash?
This lab requires onion bulbs, water, small cups or beakers, toothpicks, razor blades, microscope slides and cover slips, 70 percent isopropyl alcohol, hydrochloric acid, ethyl alcohol, Carnoy’s solution, and aceto orcein stain.

What stain is used for onion root tip mitosis squashes?
Onion root tip mitosis squashes are commonly stained with aceto orcein or acetocarmine to make chromosomes visible during the stages of mitosis.

What are the steps in the onion root tip mitosis squash preparation protocol?
The procedure includes growing onion roots, cutting and preserving the root tips, treating the tissue with acid and alcohol solutions, staining the cells, chopping the root tip, and gently squashing the tissue under a cover slip to spread the cells.

Why are my chromosome squashes unclear or difficult to see?
Common issues include insufficient chopping of the root tip, too much or too little pressure during the squash, overstaining or understaining, or using root tips that are not actively dividing.




Genetics Problems and Activities for Biology Interactive Notebooks, Warm Ups, and Bell Ringers


Genetics is the name, and warm ups, bell ringers and interactive notebook pages is the game.  

This idea is on fire in my standard biology classes!  I admit that my students were dubious (at best) at first, but now all are on board, and I am loving the daily routine.  I would call what I am doing a "warm up notebook."  The short review that each page provides for my students each day is proving to be invaluable.  But there are so many other uses for these activity pages.  They make fantastic homework assignments or short daily quizzes.  They are perfect for your science interactive notebooks.  And my students are starting to realize that their notebook is going to be awesome in December when it is time to study for my semester exam.

In earlier blog posts, I wrote about how to set up the notebooks, and pretty much exhausted the topic of the merits of these warm up /bell ringer activities.  You can check out the earlier blog posts by clicking these links:

The latest topic to be added to my bell ringer arsenal is Genetics.   Here's a preview of what is included:
 

I have divided the pages into three different categories:




There are 34 pages for the student.  Each printed page has two identical warm ups.  The only thing you have to do is print the pages and cut them in half.  Complete answer keys are also included.


A couple of examples of student work....



I hope that I have given you some new ideas for your classroom, and I hope you are having a wonderful school year.  Here are the links to the warm ups I have posted to date:



Secondary Teacher Labor Day Blog Hop


What will you be doing on Labor Day?

Teachers in my district are in their 4th week of school already.  It is time for a break!  I am teaming up with a fantastic group of middle and high school teachers to participate in the Labor Day Labor Saving Products for Teachers blog hop.   Here is the idea behind this secondary blog hop.  We want you to have a restful Labor Day, so each of us is featuring a "no prep required" product or lesson.  We have already done the work so you don't have to!

My friend, Tammy of Teaching FSL, made the button above.  She is Canadian, thus the spelling of "labour."


I would think that almost every science teacher will mention the scientific method during the first week of their class.  

Be sure to grab my Scientific Method PowerPoint.  It has 26 slides and comes with a set of notes for the teacher, and an outline for the student.  The student will fill in the outline as the lesson is being taught.  This lesson goes behind just listing the steps to the scientific method. Students will be taught how to practice and apply the scientific method to a question or problem.


It doesn't get more labor-saving than this!  Simply download this freebie, print the handouts, and you are all set to go.


Another labor-saving product that I would like to feature is my Cell Organelle Mix-Match Game.  It comes with 25 organelle cards and 112 answer/description cards.  Students have to match up the answers to the correct organelle.

The beauty of this product is that it can be used with a WIDE variety of grade levels and ability levels.  The answer cards range in difficulty from easy to hard.  You simply select the answer cards that are best suited for your students.  This game can be used with beginning life science students all the way to AP biology students.






You can be ready to use this with your class in a matter of minutes.  Simply print, cut, laminate (if you want to be fancy!), and distribute to your class. The kids will love it and you will love how much they learn!
Happy Labor Day!